{"id":4044,"date":"2020-10-06T01:06:31","date_gmt":"2020-10-06T01:06:31","guid":{"rendered":"https:\/\/www.animalhealthfoundation.net\/blog\/?p=4044"},"modified":"2020-10-06T01:06:31","modified_gmt":"2020-10-06T01:06:31","slug":"mast-cell-tumors","status":"publish","type":"post","link":"https:\/\/www.animalhealthfoundation.org\/blog\/2020\/10\/mast-cell-tumors\/","title":{"rendered":"Mast Cell Tumors"},"content":{"rendered":"<p><main id=\"MainContent\" class=\"main-content js-focus-hidden\" tabindex=\"-1\" role=\"main\"><\/p>\n<article class=\"page-width\">\n<div class=\"grid\">\n<div class=\"grid__item medium-up--five-sixths medium-up--push-one-twelfth\">\n<div id=\"shopify-section-article-template\" class=\"shopify-section\">\n<div class=\"section-header text-center\">\n<h1 class=\"article__title\"><span class=\"article__author\" style=\"font-size: 16px;\">by Judy Morgan<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><span class=\"article__date\" style=\"font-size: 16px;\"><time datetime=\"2020-09-28T16:36:38Z\">September 28, 2020<\/time><\/span><\/h1>\n<\/div>\n<div class=\"rte\">\n<p>The dreaded diagnosis: mast cell tumor.\u00a0Mast cell tumors are the most common malignant tumors in dogs, but are rare in cats.\u00a0Mast cell tumors can be quiet, locally aggressive, or spread like wildfire. They are great imitators, sometimes appearing to be small, benign growths or skin tags. They can look and feel like a lipoma or benign mass under the skin or they can be pink, raised, ulcerated, and swollen. They may grow and shrink, only to enlarge again later. It is impossible to know whether your pet&#8217;s mass is a mast cell tumor without looking at cells under the microscope.<\/p>\n<p>Healthy normal mast cells form part of the body\u2019s immune system. They can be found in most tissues, but in particular in the skin and the linings of the digestive tract, lungs, mouth and the nose.\u00a0They are also involved in allergies and allergic reactions.\u00a0When triggered, the mast cells release large amounts of heparin, histamine, and enzymes.<\/p>\n<p>Mast cell tumors are generally easy to diagnose. A sampling of cells from an impression smear or a fine needle aspirate can be stained and examined under a microscope in your veterinarian&#8217;s office or sent to a pathology lab for path review. The cells are distinct in appearance, being filled with dark purple granules. Generally, when a mast cell mass is aspirated, the cells will release those granules, resulting in purple spots all over the microscope field. While it is possible to say this IS a mast cell tumor, it is not possible to determine how aggressive the mass will be without a biopsy.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0246\/6542\/3950\/files\/mast_cells_480x480.jpg?v=1601306941\" alt=\"\" width=\"150\" height=\"200\" \/><\/p>\n<p>The cause of mast cell tumors is up for debate, just like many cancers. Immune-system suppression or dysfunction and over-vaccination have been implicated by some researchers.<\/p>\n<p>Treatment consists of surgical removal with wide margins. This can be difficult when tumors are located in areas such as limbs where there will not be enough skin to close over areas of wide excision. Biopsy of the mass will determine the grade of the tumor to help predict how the tumor will behave and whether clean margins were realized during surgery.\u00a0Grade 1 tumors can usually be removed and normally they do not return.\u00a0Only about 5 to 10% of Grade 2 tumors will return if surgery is done with a wide excision, but about 50% of Grade 3 tumors will return after surgical removal, even with clean margins.<\/p>\n<p>Chemotherapy and radiation may be recommended for higher grade tumors. Unfortunately, there is certainly no guarantee these options will prevent recurrence. Many clients come to my office looking for alternative options to help slow the growth of these masses. While each pet is different, I have a few recommendations that I generally recommend.<\/p>\n<ul>\n<li>A clean, commercial\u00a0<a href=\"https:\/\/allprovide.com\/\" aria-describedby=\"a11y-external-message\">human-grade<\/a>, whole-food diet low in starchy carbs or a\u00a0<a href=\"https:\/\/drjudymorgan.com\/blogs\/blog\/feed-the-dog-not-the-cancer?_pos=2&amp;_sid=96616c371&amp;_ss=r\">home-prepared diet<\/a>, or a\u00a0<a href=\"https:\/\/www.ketopetsanctuary.com\/#description\" aria-describedby=\"a11y-external-message\">ketogenic diet<\/a>.<\/li>\n<li><a href=\"https:\/\/drjudymorgan.com\/products\/palmitoylethanolamide-120-count?_pos=1&amp;_sid=d9f05b26b&amp;_ss=r\">Palmitoylethanolamide<\/a>\u00a0or\u00a0<a href=\"https:\/\/drjudymorgan.com\/products\/palmitoylethanolamide-120-count?_pos=1&amp;_sid=65b6e593e&amp;_ss=r\">PEA<\/a>, which is a fatty acid amide that supports the healthy function of mast cells and decreases inflammation and granule release.<\/li>\n<li><a href=\"https:\/\/naturallyhealthyhemp.com\/\" aria-describedby=\"a11y-external-message\">Cannabidiol,<\/a>\u00a0which helps block pain and inflammation through cannabinoid receptors. There is some evidence that CBD can have an\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32340151\/\" aria-describedby=\"a11y-external-message\">anti-tumor effect<\/a>\u00a0as well.<\/li>\n<li><a href=\"https:\/\/drjudymorgan.com\/products\/dr-harveys-solaris-supplement?_pos=1&amp;_sid=3ffdbb2d0&amp;_ss=r\">Mushroom supplements<\/a>\u00a0for their cancer-fighting aspects. Mushrooms fight cancer in four specific ways: They stimulate the immune system, help immune cells bind to tumor cells, reduce the number of cancer cells (cytotoxic effect), and slow down cancer cell growth.\u00a0The Japanese government officially recognizes\u00a0<a href=\"https:\/\/www.eurekalert.org\/pub_releases\/2018-08\/fefu-mot080218.php\" aria-describedby=\"a11y-external-message\">mushroom cancer therapy<\/a>\u00a0as a treatment.<\/li>\n<li><a href=\"https:\/\/drjudymorgan.com\/products\/iceland-pure-unscented-salmon-oil?_pos=1&amp;_sid=d4029017a&amp;_ss=r\">Omega-3 fatty acids<\/a>\u00a0to decrease pain and inflammation. Omega-3&#8217;s work in\u00a0<a href=\"https:\/\/medicalxpress.com\/news\/2018-07-products-omega-fatty-acid-metabolism.html\" aria-describedby=\"a11y-external-message\">conjunction\u00a0<\/a>with the endocannabinoid system to decrease spread of cancer throughout the body.<\/li>\n<li>IP-6 400 to 800 mg daily &#8211; an antioxidant that plays and important role in regulating vital cellular functions, helps reduce tumor size and prevent spread<\/li>\n<li>Artemisinin &#8211; also known as sweet wormwood, 100 mg twice daily for 11 days on, 3 days off, repeat.\u00a0Cancer cells take up more iron then normal cells. Artemisinin is attracted to these high iron cells and selectively goes to them. Once inside the cancer cells it reacts with the iron causing free-radical formation which kills the cancer cells.<\/li>\n<li>Xue Fu Zhu Yu Tang &#8211; Mast cell\u00a0cancer often arises if there is impaired blood flow to the skin. Without good blood flow the immune system cannot find and destroy the cancer cells that arise.\u00a0This herb helps promote blood flow to the skin so the immune system can reach the mast cell cancer. In my experience this formula helps to reduce tumor size, occasionally shrink the small tumors completely and prevent formulation of new mast cell tumors.<\/li>\n<li><a href=\"https:\/\/drjudymorgan.com\/products\/kin-kind-hip-joint-supplement?_pos=2&amp;_sid=ee76288b8&amp;_ss=r\">Golden paste<\/a>\u00a0&#8211; turmeric has been shown to have cancer-fighting abilities. It is synergistic with the Xue Fu Zhu Yu Tang.<\/li>\n<\/ul>\n<p>From a traditional veterinary medicine standpoint, these tumors are commonly treated using steroids (prednisone, dexamethasone) and antihistamines (most commonly diphenhydramine). Side effects from long-term use of these drugs make them a poor choice for ongoing management, but they may have short-term benefits that might be worthwhile.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"text-center return-link-wrapper page-width\">About Dr. Morgan<\/div>\n<p><\/main><\/p>\n<div id=\"shopify-section-footer\" class=\"shopify-section\">\n<footer class=\"site-footer\" role=\"contentinfo\">\n<div class=\"page-width\">\n<div class=\"site-footer__content\">\n<div class=\"site-footer__item\n\n                    site-footer__item--one-half\n                    \"><\/p>\n<div class=\"site-footer__item-inner site-footer__item-inner--text\">\n<div class=\"site-footer__rte\n                              \"><\/p>\n<p>Dr. Judy Morgan is a nationally renowned author and veterinarian certified in acupuncture, food therapy, and chiropractic care for dogs, cats, and horses. As a sought after speaker, Dr. Morgan shares her insight here with\u00a0blogs and videos.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/footer>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>by Judy Morgan\u00a0September 28, 2020 The dreaded diagnosis: mast cell tumor.\u00a0Mast cell tumors are the most common malignant tumors in dogs, but are rare in cats.\u00a0Mast cell tumors can be quiet, locally aggressive, or spread like wildfire. They are great imitators, sometimes appearing to be small, benign growths or skin tags. They can look and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-4044","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mast Cell Tumors | The Animal Health Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.animalhealthfoundation.org\/blog\/2020\/10\/mast-cell-tumors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mast Cell Tumors | The Animal Health Foundation\" \/>\n<meta property=\"og:description\" content=\"by Judy Morgan\u00a0September 28, 2020 The dreaded diagnosis: mast cell tumor.\u00a0Mast cell tumors are the most common malignant tumors in dogs, but are rare in cats.\u00a0Mast cell tumors can be quiet, locally aggressive, or spread like wildfire. They are great imitators, sometimes appearing to be small, benign growths or skin tags. 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